In the milk, there is butter, but if you want concentrated butter, you have to churn milk and take out the butter. Similarly, Krishna is spread everywhere by different potencies but when there is question of love, we have to be in direct touch with Krishna. That is personalism. The heat of the impersonalist sunshine and the heat in the sun globe is far different. One who is in personal touch with Krishna, their spiritual bliss is incomparable. The spiritual bliss derived from impersonalist realization is just like a drop of water in the presence of the Atlantic Ocean. That is the difference between personalism and impersonalism.
From Srila Prabhupada's letter to: Gurudasa — Los Angeles 14 December, 1968