First birth is from your parents but real birth, real life, begins when one accepts a bona fide spiritual master and renders service onto him. Then the path is open for going back to home, back to Godhead, to live eternally in full knowledge and full bliss and in association with the Supreme Personality of Godhead Himself, Lord Krishna.
From Srila Prabhupada’s letter to Narayani — Bombay, India 11 June, 1971