The word niskincanasya refers to a person who has finished his material activities. Such a person can begin to execute his activities in Krsna consciousness to cross over the ocean of nescience. It is very dangerous for such a person to have intimate relationships with mundane people or to become intimately related with women. This formality is to be observed by anyone who is serious about going back home, back to Godhead. To teach His personal associates these principles, Sri Caitanya Mahaprabhu expressed external anger when touched by the King. Since the Lord was very much satisfied with the humble behavior of the King, He intentionally allowed the King to touch Him, but externally He expressed anger just to warn His personal associates. Greatly lamenting, the Lord then informed Sarvabhauma Bhattacarya, “‘Alas, for a person who is seriously desiring to cross the material ocean and engage in the transcendental loving service of the Lord without material motives, seeing a materialist engaged in sense gratification or seeing a woman who is similarly interested is more abominable than drinking poison willingly.'”
Srila Prabhupada, CC Madhya 11.8, purport