It is natural for those who have developed intense love for Krsna not to care for personal inconvenience and impediments. Such devotees are simply determined to execute the order of the Supreme Personality of Godhead or His representative, the spiritual master. In all circumstances, even amidst the greatest dangers, they undeviatingly carry on with the greatest determination. This definitely proves the intense love of the servitor. As stated in Srimad-Bhagavatam (10.14.8), tat te ‘nukampam su-samiksamanah: those who seriously desire to get free from the clutches of material existence, who have developed intense love for Krsna, are worthy candidates for going back home, back to Godhead. An intense lover of Krsna does not care for any number of material discomforts, scarcity, impediments or unhappiness. It is said that when one sees apparent unhappiness or distress in a perfect Vaisnava, it is not at all unhappiness for him; rather, it is transcendental bliss. In the Siksastaka (8), Sri Caitanya Mahaprabhu has also instructed, aslisya va pada-ratam pinastu mam [Cc. Antya 20.47]. The intense lover of Krsna is never deviated from his service, despite all difficulties and impediments brought before him.

Srila Prabhupada, Cc Madhya 4.187 purport