Caitanya Mahaprabhu sent Sanatana Gosvami to Vrndavana, and other Gosvami, Rupa Gosvami…

mathurate pathaila rupa-sanatana
dui sena-pati kaila bhakti pracarana
[Cc Adi 7.164]

Sena-pati means these two brothers, Rupa Gosvami and Sanatana Gosvami, were appointed as the commander-in-chief, commander-in-chief in this fighting with maya. This Krsna consciousness means it is declaration of fighting with maya. Maya is killing all the poor conditioned souls, and Caitanya Mahaprabhu declared war against maya by spreading Krsna consciousness. And the commander-in-chiefs are Rupa-Sanatana. In other words, if anyone wants to be expert in Krsna consciousness to fight with maya, they must follow the principles of Rupa Gosvami and Sanatana Gosvami.

From Srila Prabhupada’s lecture on Sri Caitanya-caritamrta, Adi-lila 7.149–171 – March 18, 1967, San Francisco